We are always looking for highly-motivated individuals to join the LCPO! Interested undergraduate and graduate students can apply to the following offers. They are also strongly encouraged to contact LCPO's researchers directly.

M2 Internship - Thermoresponsive copolypeptides: advanced building blocks for nanomaterials

M2 Internship - Thermoresponsive copolypeptides: advanced building blocks for nanomaterials figure

Category: Internship

Duration: 6 months

Team: Polymer self-assembly and life sciences

Salary: 591 €

Laboratory: LCPO

Contacts : Colin Bonduelle

Project summary

Proteins are some of nature’s most versatile materials, expressing almost all the functions of living forms. Although their use in material science remains
challenging, they have inspired the use of their synthetic analogues, polypeptides, which also use amino acids as monomers. These can be produced  by a simple polymerization process while also being biocompatible and biodegradable. The living ring opening polymerization (ROP) of N-carboxyanhydrides (NCAs) is the most prominent method to produce polypeptides that can mimic some of the properties and functions of natural  proteins. These can self-organize into ordered nanostructures and are widely used in biomedicine and nanotechnology. This internship will contribute to a research project focused on the copolymerization of these monomers into polymeric scaffolds with a controlled microstructure. The goal is to produce stimuli-responsive (smart) copolypeptides from naturally occurring amino acids and study their thermoresponsive properties.

 

CONTACT :

Dr Colin Bonduelle (colin.bonduelle@enscbp.fr) and Dr Simon Harrisson (simon.harrisson@enscbp.fr)