Category: Faculties
Status: Researcher
Employer: CNRS
Team: Polymer self-assembly and life sciences
Location: ENSMAC, Office N2-27
+33 5 56 84 79 56
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Dr. Chloé Grazon develops nanobiophotonic probes, i.e. nanoparticles that interact with light and are able to sense events at the biological level, for bioanalytics and bioimaging. Her current research includes the design, synthesis,functionalization and spectroscopic characterization of ultrabright polymer nanoparticles.
Key research areas: Fluorescent nanoparticles, FRET, Biosensors, PISA, Biohybrids (DNA, proteins...), Polymer synthesis
Dr. Chloé GRAZON received her engineering degree from ESPCI Paris (France) in 2009 after initial studies at the University of Rennes. She then pursued a Ph.D. in chemistry at ENS Cachan (France) - PPSM under the supervision of Dr. Rachel Méallet-Renault and Dr. Gilles Clavier, in collaboration with Dr. Jutta Rieger and Prof. Bernadette Charleux. Her doctoral research focused on the synthesis of fluorescent polymer nanoparticles, synthesized by a one-pot RAFT miniemulsion polymerization process to produce highly stable and bright core–shell nanoparticles.
Following her Ph.D., she worked 5 years in industry, first as a research engineer at L’Oréal (France) and then in a start-up (Nexdot), where she developped polymer ligands for quantum dots used in imaging and display technologies.
In 2017, she was awarded a 3 years Marie Skłodowska-Curie fellowship, allowing her to carry out postdoctoral research between Boston University (USA) under the supervision of Prof. Mark W. Grinstaff and the University of Bordeaux (France) with Dr. Sébastien Lecommandoux. During this period, she developed biosensors based on fluorescent nanoparticles and novel synthetic approaches for polypeptide-based nanomaterials.
In 2020, she joined the CNRS as a permanent researcher at ISM (University of Bordeaux, France) and in 2026 she moved to the LCPO. Her current research focuses on the design, self-assembly, and photophysical properties of organic fluorescent nanoparticles for applications as optical biosensors. Her work, at the interface between polymer chemistry and photophysics, has been supported by an ERC Starting Grant (COMET project) in 2022 and recognized by the CNRS Bronze Medal in 2025
Chloé Grazon received an ERC St Grant in 2022, the Young Researcher Prize in Physical Chemistry in 2023 and the CNRS Bronze medal in 2025
Scientific Outreach:
Highlighted papers by the CNRS:
Green synthesis and self-assembly for polypeptides
Organic photocatalysts to product green hydrogen
Towards greener chemistry labs
Journal covers:
Ji Sifan, Lecommandoux Sébastien, Bonduelle Colin, Grazon Chloé
Journal title: Journal of materials chemistry B https://hal.science/hal-05578224/document 10.1039/d5tb02566d (2026)
Beauseroy Hannah, Grazon Chloé, Antoine Segolene, Badreldin Mostafa, Salas-Ambrosio Pedro, Harrisson Simon, Garanger Elisabeth, Lecommandoux Sebastien, Bonduelle Colin
Journal title: Macromolecular Rapid Communications, Volume(s): 45, Issue(s): 14, Page(s): 2400079 https://hal.science/hal-04649380/document 10.1002/marc.202400079 (2024)
Grazon Chloé, Garanger Elisabeth, Lalanne Pierre, Ibarboure Emmanuel, Galagan James E, Grinstaff Mark W, Lecommandoux Sébastien
Journal title: Biomacromolecules, Volume(s): 24, Issue(s): 11, Page(s): 5027-5034 https://hal.science/hal-04263919/document 10.1021/acs.biomac.3c00662 (2023)
