Sébastien Lecommandoux

Sébastien Lecommandoux picture

Category: Faculties

Status: Full professor

Employer: Bordeaux INP

Team: Leader Polymer self-assembly and life sciences

Location: ENSCBP building A, office N1-44

33 (0)5 56 84 66 03

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Key Research Areas : Smart polymersomes – Polypeptide and polysaccharide synthesis – Block copolymer self-assembly – Biomimicry for (bio)materials design – Drug-delivery systems – Cancer therapy – Theranostics

Resume

Education and experience

Sébastien Lecommandoux received his PhD degree in Chemistry and Physics in 1996 at the University of Bordeaux, supervised by Pr F. Hardouin (CRPP). Then, he went to the Materials Research Laboratory and the Beckman Institute (University of Illinois at Urbana-Champaign, USA) and worked as a Post-Doc in the group of Pr S. I. Stupp. Here, he learned the art of self-assembly and supramolecular chemistry. Subsequently, he joined the LCPO as Associate Professor in 1998, and became Professor in 2005 and Full Professor in 2009. His current research interests include polypeptide and polysaccharide based block copolymers design and self-assembly, biomimetic approaches toward design of compartmentalized polymersomes as synthetic viruses and artificial cells, as well as the design of biomimetic polymersomes for drug-delivery and theranostic for smart therapeutics, mainly in cancer.

Achievement and functions

Pr Sébastien Lecommandoux is currently Director of the Laboratoire de Chimie des Polymères Organiques (LCPO-CNRS) and is leading the group “Polymers Self-Assembly and Life Sciences”. He trained 30 PhD students and supervised 32 postdoctoral researchers over the last 20 years, and was coordinator of more than 50 national and international research grants. He developed important interactions with industries in the field of pharmaceutical, biomaterial and cosmetic science, and is currently director of a joint laboratory between LCPO and L’OREAL. He also organized many international conferences and symposia, including Bordeaux Polymer Conferences, ACS, MRS, EPF…

Sébastien Lecommandoux is recipient of the CNRS bronze medal (2004), Institut Universitaire de France Junior Chair (IUF 2007), Fellow of the Royal Society of Chemistry RSC (2017), Seqens Award of the French Academy of Science (2019). He is Editor-in-Chief of Biomacromolecules (ACS) since 2020 after being Associate Editor since 2013. He is also in the Editorial Advisory Board of several international journals, including Bioconjugate Chemistry (ACS), Polymers (MDPI), Polymer Chemistry (RSC) and Biomaterials Science (RSC).

Teaching activities

Polymer science program at the ENSCBP and biological chemistry at the University of Bordeaux.

Scientific production

Pr Sébastien Lecommandoux has published more than 180 publications in international journal and 6 book chapters, with over 13000 citations (h-factor 57, Google Scholar). He presented more than 260 oral presentations, including 230 on invitation, including 10 plenary and keynote lectures. He edited a book on Block Copolymers in Nanoscience and is the co-inventor of 10 patents, 4 being licensed to cosmetic or pharmaceutical companies.

Latest publications

  • Surface Immobilized Nucleic Acid–Transcription Factor Quantum Dots for Biosensing figure

    Surface Immobilized Nucleic Acid–Transcription Factor Quantum Dots for Biosensing Journal article

    Chen Mingfu, Nguyen Thuy, Varongchayakul Nitinun, Grazon Chloé, Chern Margaret, Baer R., Lecommandoux Sébastien, Klapperich Catherine, Galagan James, Dennis Allison, Grinstaff Mark

    Journal title: Advanced Healthcare Materials, Volume(s): 9, Issue(s): 17, Page(s): 2000403 https://hal.archives-ouvertes.fr/hal-02904157/document 10.1002/adhm.202000403 (2020)

  • Thermoinduced Crystallization-Driven Self-Assembly of Bioinspired Block Copolymers in Aqueous Solution figure

    Thermoinduced Crystallization-Driven Self-Assembly of Bioinspired Block Copolymers in Aqueous Solution Journal article

    Wang Zhiwei, Lin Min, Bonduelle Colin, Li Rongye, Shi Zhekun, Zhu Chenhui, Lecommandoux Sébastien, Li Zhibo, Sun Jing

    Journal title: Biomacromolecules, Volume(s): 21, Issue(s): 8, Page(s): 3411-3419 10.1021/acs.biomac.0c00844 (2020)

  • Hyaluronic acid presentation at the surface of self‐assembled nanoparticles transforms a hyaluronidase HYAL1 substrate into an efficient and selective inhibitor figure

    Hyaluronic acid presentation at the surface of self‐assembled nanoparticles transforms a hyaluronidase HYAL1 substrate into an efficient and selective inhibitor Journal article

    Duan Haohao, Donovan Mark, Hernandez Franck, Di Primo Carmelo, Garanger Elisabeth, Schultze Xavier, Lecommandoux Sébastien

    Journal title: Angewandte Chemie International Edition, Volume(s): 59, Issue(s): 32, Page(s): 13591-13596 https://hal.archives-ouvertes.fr/hal-02561770/document 10.1002/anie.202005212 (2020)