Status: Full professor
Employer: Bordeaux INP
Team: Leader Polymer self-assembly and life sciences
Location: ENSCBP building A, office N1-44
33 (0)5 56 84 66 03
Key Research Areas : Smart polymersomes – Polypeptide and polysaccharide synthesis – Block copolymer self-assembly – Biomimicry for (bio)materials design – Drug-delivery systems – Cancer therapy – Theranostics
Education and experience
Sébastien Lecommandoux received in 1996 his PhD in Physical Chemistry from the University of Bordeaux. After a postdoctoral experience at the University of Illinois (UIUC, USA) in the group of Prof. Samuel I. Stupp, he started his academic career at the Laboratoire de Chimie des Polymères Organiques as Associate Professor in 1998 and was promoted to Full Professor at Bordeaux INP in 2005. He is currently Director of the Laboratoire de Chimie des Polymères Organiques (LCPO-CNRS) and is leading the group “Polymers Self-Assembly and Life Sciences”. His research interests include polypeptide and polysaccharide-based block copolymers self-assembly, the design of polymersomes for drug-delivery and theranostic, as well as biomimetic approaches toward design of synthetic viruses and artificial cells. He has published more than 180 papers in international journal with more than 16,000 citations (h-index 63), 7 book chapters and 12 patents (2 being licenced, 1 start-up created). Sébastien Lecommandoux is recipient of the CNRS bronze medal (2004), Institut Universitaire de France Junior Chair (IUF 2007), Fellow of the Royal Society of Chemistry RSC (2017), Seqens Award of the French Academy of Science (2019), Member of the Academia Europaea (2020). He is Editor-in-Chief of Biomacromolecules (ACS) since 2020 after being Associate Editor since 2013. He is also in the Editorial Advisory Board of several international journals, including Bioconjugate Chemistry (ACS), Polymer Chemistry (RSC) and Biomaterials Science (RSC).
Achievement and functions
Pr Sébastien Lecommandoux is currently Director of the Laboratoire de Chimie des Polymères Organiques (LCPO-CNRS) and is leading the group “Polymers Self-Assembly and Life Sciences”. He trained 30 PhD students and supervised 32 postdoctoral researchers over the last 20 years, and was coordinator of more than 50 national and international research grants. He developed important interactions with industries in the field of pharmaceutical, biomaterial and cosmetic science, and is currently director of a joint laboratory between LCPO and L’OREAL. He also organized many international conferences and symposia, including Bordeaux Polymer Conferences (Chair of editions 2018 and 2022), ACS, MRS, EPF… Sébastien Lecommandoux is recipient of the CNRS bronze medal (2004), Institut Universitaire de France Junior Chair (IUF 2007), Fellow of the Royal Society of Chemistry RSC (2017), Seqens Award of the French Academy of Science (2019), Member of the Academia Europaea (2020). He is also currently Advisory Professor at the Japan Advanced Institute of Science and Technology (JAIST), Japan. He is also Editor-in-Chief of Biomacromolecules (ACS) since 2020 after being Associate Editor since 2013. He is also in the Editorial Advisory Board of several international journals, including Bioconjugate Chemistry (ACS), Polymer Chemistry (RSC) and Biomaterials Science (RSC).
Appointed to the ENSCBP, I have always taught mainly in this generalist engineering school in chemistry and physics (and more recently in biology). My teaching is mainly dedicated to polymer science with a homogeneous distribution over the 3 years of engineering training, including lectures, tutorials and practical work. I have also participated for a long time in the Bachelor and Master courses of the University of Bordeaux, bringing my experience in the field of block copolymers, physical chemistry and the interface with biology. Moreover, I assumed various responsibilities in the organization of the teaching activities, with in particular the responsibility for the practical work in polymers of the ENSCBP (1999-2006), the responsibility for the teachings in 1st year of the ENSCBP (2003-2006) and the structuration and responsibility of the 3rd year teaching program at ENSCBP about "engineering of polymers and formulation" (2000-2006).
Pr Sébastien Lecommandoux has published more than 200 publications in international journal and 6 book chapters, with over 16000 citations (h-factor 63, Google Scholar). He presented more than 260 oral presentations, including 230 on invitation, including 11 plenary and keynote lectures. He edited a book on Block Copolymers in Nanoscience and is the co-inventor of 12 patents, 2 being licensed to cosmetic or pharmaceutical companies. (See resume for detailed list of scientific production)
Robust Polyion Complex Vesicles (PICsomes) based on PEO‐b‐Poly(Amino Acid) Copolymers Combining Electrostatic and Hydrophobic Interaction: Formation, siRNA Loading and Intracellular Delivery Journal article
Light-Responsive Elastin-Like Peptide-Based Targeted Nanoparticles for Enhanced Spheroid Penetration. Journal article
Le Duc H T, Ibrahimova Vusala, van den Wildenberg Sebastian a H, Wu Hanglong, Fonseca Alba, Torres Tomas, Garanger Elisabeth, Leenders William P J, Brock Roland, Lecommandoux Sébastien, van Hest Jan C M